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Understanding Hormones and Their Role in PCOS and PCOD

  • Writer: Dr Rambeti Chauhan
    Dr Rambeti Chauhan
  • Jan 28
  • 4 min read

Polycystic Ovary Syndrome (PCOS) and Polycystic Ovarian Disease (PCOD) are two conditions that impact millions of women worldwide. While the terms are often used interchangeably, they have slight differences in nature and severity. One thing they share, though, is a major cause—hormonal imbalances. But what exactly are these hormonal disruptions, and how do they influence PCOS and PCOD?

In this blog, we’ll break down the role of hormones in these conditions, helping you better understand what’s happening in your body and why it matters.

What is PCOS and PCOD?

PCOS:

Polycystic Ovary Syndrome (PCOS) is primarily a hormonal disorder that affects the ovaries and overall endocrine system. Women with PCOS often have elevated levels of male hormones (androgens), which lead to irregular menstrual cycles, ovulation problems, and symptoms like acne, excessive facial hair, and weight gain.

PCOD:

Polycystic Ovarian Disease (PCOD), meanwhile, is more of a disorder involving enlarged ovaries that produce immature or partially-mature eggs. These eggs can accumulate, forming cysts. Like PCOS, hormonal imbalances play a role in PCOD as well, although its symptoms and health effects can be more manageable in comparison to PCOS.

The Hormones at Play

Insulin and Its Influence:

One of the most significant contributors to PCOS/PCOD symptoms is insulin, a hormone produced by the pancreas that regulates blood sugar levels. Many women with PCOS or PCOD have insulin resistance, meaning their bodies don't respond effectively to insulin.

When the body struggles to process insulin, glucose levels spike, leading to increased fat storage and other complications. High insulin levels also trigger excess androgen production, exacerbating symptoms like unwanted hair growth and irregular periods.

Androgens (Male Hormones):

Elevated androgen levels are a hallmark of PCOS. While androgens (including testosterone) naturally occur in small amounts in women, an overproduction disturbs menstrual cycles and affects ovulation. High androgen levels can also affect hair follicles, leading to acne and excess hair growth in places like the face and chin (hirsutism).

LH and FSH (Luteinizing Hormone and Follicle-Stimulating Hormone):

LH and FSH are crucial hormones for ovulation. Imbalances between the two can result in dysfunction in egg release, one of the characteristic symptoms of PCOS/PCOD. For many women with these conditions, the body produces too much LH compared to FSH.

This imbalance contributes to the formation of ovarian cysts and prevents the ovaries from releasing eggs properly.

Estrogen and Progesterone:

Estrogen and progesterone are the primary female hormones responsible for regulating the menstrual cycle. Women with PCOS/PCOD often experience disruptions in the balance of these hormones. Such disruptions can lead to skipped ovulation or periods, sometimes going months without menstruation.

Cortisol and Stress Hormones:

Stress-related hormones like cortisol can exacerbate PCOS/PCOD symptoms. Chronic stress influences the production of cortisol, which in turn can influence insulin sensitivity and androgen levels. This is why stress management is often an essential part of managing these conditions.

The Effects of Hormonal Imbalances in PCOS/PCOD

When these hormones fall out of balance, they create a domino effect in the body, leading to the key symptoms of PCOS/PCOD, including:

  • Irregular Periods: Disrupted ovulation causes inconsistent or missed periods.

  • Infertility: The absence of ovulation can make it challenging to conceive.

  • Weight Gain and Difficulty Losing Weight: High insulin levels and a slower metabolism contribute to weight challenges.

  • Hirsutism: Excess facial or body hair driven by elevated androgen levels.

  • Oily Skin and Acne: Hormonal fluctuations stimulate oil production, clogging pores and causing breakouts.

Cysts in the Ovaries: Immature and unreleased follicles accumulate, forming fluid-filled cysts.

Managing Hormonal Imbalances in PCOS/PCOD

Although there’s currently no cure for PCOS/PCOD, lifestyle changes and medical interventions can help manage the symptoms by addressing these hormonal imbalances.

1. Diet and Nutrition:

A low-glycemic, nutrient-rich diet can stabilize blood sugar, reduce insulin resistance, and balance hormones. Foods like leafy greens, whole grains, lean proteins, and healthy fats are excellent choices.

2. Regular Exercise:

Physical activity improves insulin sensitivity and helps with weight management. Both moderate aerobic exercises (like walking or swimming) and strength training are beneficial.

3. Stress Management:

Practices like yoga, meditation, and mindfulness techniques can ease stress, lowering cortisol levels and minimizing their impact on hormonal imbalances.

4. Medications:

Doctors may recommend medications like metformin to regulate insulin or hormonal birth control to balance estrogen and progesterone levels. Always consult a healthcare provider for personalized treatment plans.

5. Supplements:

Some women find relief with supplements like inositol, omega-3 fatty acids, or vitamin D. However, it’s essential to consult a healthcare professional before starting any supplements.

6. Medical Treatments:

If fertility is a concern, treatments like ovarian drilling or medications like clomiphene can encourage ovulation.

Final Thoughts

Understanding the role of hormones in PCOS and PCOD is key to managing these conditions effectively. While they can present significant challenges, proactive lifestyle changes, medical guidance, and consistent care can help mitigate symptoms and improve quality of life.

If you suspect you have PCOS or PCOD or you're currently managing symptoms, don’t hesitate to reach out to your doctor or endocrinologist. Early intervention and a personalized approach can make a world of difference


 
 
 

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